Unlocking Biological Insights Through AI-driven Multi-Omics Integration.
Poster presented at the Spanish Drug Discovery Network conference 2025.
Publications
The value of subcutaneous xenografts for individualised radiotherapy in HNSCC: Robust gene signature correlates with radiotherapy outcome in patients and xenografts.
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR-and RAR-dependent transcription.
Patil, S., et al. (2024). "ALDH1A1 drives prostate cancer metastases and radioresistance." Theranostics, 14, 714-732.
Identified ALDH1A1 as a key driver of prostate cancer metastasis and radioresistance through its interaction with androgen receptor and retinoic acid receptor-dependent transcription pathways.
Molecular characterisation of tumours and biomarker identification for personalised radiation oncology using genomic data of patients with locally advanced head and neck squamous cell carcinoma.
This is my PhD thesis conducted in the Modeling and Biostatistics in Radiation Oncology group at OncoRay – National Center for Radiation Research in Oncology under the supervision of Prof. Dr. Steffen Löck.
A Novel 2-Metagene signature to identify high-risk HNSCC patients amongst those who are clinically at intermediate risk and are treated with PORT.
Patil, S., et al. (2022). "A Novel 2-Metagene signature to identify high-risk HNSCC patients." Cancers, 14(12), 3031.
Developed a novel 2-metagene signature for risk stratification in head and neck squamous cell carcinoma (HNSCC) patients receiving postoperative radiotherapy, enabling personalized treatment decisions.
Development and validation of a 6-gene signature for the prognosis of loco-regional control in patients with HPV-negative locally advanced HNSCC treated by postoperative radio(chemo)therapy.
Plasticity within aldehyde dehydrogenase–positive cells determines prostate cancer radiosensitivity.
Analyses of molecular subtypes and their association to mechanisms of radioresistance in patients with HPV-negative HNSCC treated by postoperative radiochemotherapy.
Assessing the in vitro resistance development in Enterovirus 71 in the context of combination antiviral treatment.
The Role of the Virome in the Gut-Liver Axis.
This is chapter in the book “The Human Gut-Liver-Axis in Health and Disease”.
Male calling and spacing in natural chorus of Platygryllus sp. Implications for masking interference and mate choice.
This master thesis is about Male spacing in natural choruses of Platygryllus sp. of crickets and its implications on male and female crickets. The acoustic spaces of male crickets overlapped to a large extent and it is likely that the female could hear multiple males at a time. The study focuses on the strategy the female would choose to mate.